缪志江 团队成员
1、个人简历
缪志江，男，博士，讲师，硕士生导师。主要从事HDV等常见病原体的分子流行病学系统研究工作以及抗病毒研究相关课题，同时研究领域还涉及HCV、HEV、HPgV-1、HPgV-2以及轮状病毒等病原体的分子检测诊断、遗传进化分析及临床研究，具有传染病学、病原生物学、分子流行病学、分子病毒学、病毒基因组学和生物信息学等多学科专业背景，以及病毒细胞模型构建和药物筛选评价等相关方法体系和研究经验。现主持云南省科技厅重大专项课题、国家自然科学基金青年项目、云南省科技厅基础研究面上项目等。以第一作者或通讯作者在国际学术刊物发表高水平SCI论文共计10篇，其中一区1篇、二区5篇、三区3篇以及四区1篇。
2、联系方式
电话：15887862723
电子邮箱：miaozhijiang@yeah.net
通讯地址：云南省昆明市呈贡区昆明理工大学生命科学学院分子病毒学实验室
3、教育经历
2010.09-2014.06 云南师范大学，生命科学与技术学院，生物技术专业，学士
2014.09-2017.06 昆明理工大学，生命科学与技术学院，生物化学与分子生物学，硕士
2017.10-2021.09 Erasmus University Medical Center Rotterdam，Department of Gastroenterology and Hepatology，Pathogenbiology，PhD,
4、工作经历
2022.02-至今昆明理工大学生命科学与技术学院，硕士生导师
5、承担主要科研项目
1. 云南省科技厅,重大科技专项课题, 202302AA310044-01,云南省不孕不育人群中病原体分布特征和流行规律研究, 2023-06至2026-05, 447.50万元,在研,主持
2. 国家自然科学基金委员会,青年科学基金项目, 32300142,中国丁型肝炎病毒地域流行差异性及相关影响因素研究, 2024-01-01至2026-12-31, 30万元,在研,主持
3. 云南省科技厅,基础研究专项, 202401AT070407,乙型肝炎病毒天然重组包膜蛋白对丁型肝炎病毒增殖过程的影响及机制研究, 2024-03至2027-02, 10万元,在研,主持
4. 云南省第一人民医院，临床病毒学重点实验室开放课题重点项目，202205AG070061-BD-05感染性不孕不育相关肝炎病毒分子诊断方法的建立及大规模临床应用；2024-08至2027-07, 10万元,在研,主持
6、代表论文、专利和专著
1. Xiaoyan Xu1, Yunjiao Luo1, Canlin He, Ziqin Dian, Hongying Mi, Jinghui Yang, Yue Feng, Zhijiang Miao*and Xueshan Xia*, Increased Risk of Neurological Disease Following Pediatric Rotavirus Infection: A Two-Center Case-Control Study.Journal of Infectious Diseases, 2023 May 29;227(11):1313-1321.（IF=7.8; JCR Q1区/医学二区Top）
2. Zhijiang Miao, Shaoshi Zhang, Xumin Ou, Shan Li, Zhongren Ma, Wenshi Wang, Maikel P Peppelenbosch, Jiaye Liu* and Qiuwei Pan*, Estimating the Global Prevalence, Disease Progression, and Clinical Outcome of Hepatitis Delta Virus Infection.Journal of Infectious Diseases, 2020 Apr 27;221(10):1677-1687.（IF=5.2; JCR Q1区/医学二区Top）
3. Zhijiang Miao and Qiuwei Pan*. Revisiting the estimation of hepatitis D global prevalence,Journal of Hepatology, 2020 Nov;73(5):1279-1280.（Letter,IF=25.1; JCR Q1区/胃肠肝病学一区Top）
4. Zhijiang Miao, Ruyi Zhang, Peifa Yu, Yang Li, Qiuwei Pan* and Yunlong Li*. The macrolide antibiotic azithromycin potently inhibits hepatitis E virus in cell culture models,International Journal of Antimicrobial Agents, 2021 Sep;58(3):106383. (IF=15.4; JCR Q1医学二区)
5. Ziqin Dian, Yi Sun, Guiqian Zhang, Ya Xu, Xin Fan, Xuemei Yang, Qiuwei Pan, Maikel Peppelenbosch andZhijiang Miao*. Rotavirus-related systemic diseases: clinical manifestation, evidence and pathogenesis,Critical Reviews in Microbiology, 2021 Sep;47(5):580-595.（IF=7.4; JCR Q1区/微生物学二区）
6. Zhijiang Miao, Shaoshi Zhang, Zhongren Ma, Mohamad S. Hakim, Wenshi Wang, Maikel P. Peppelenbosch and Qiuwei Pan*, Recombinant identification, molecular classification and proposed reference genomes for hepatitis delta virus,Journal of Viral Hepatitis, 2019 Jan;26(1):183-190.（IF=3.6; JCR Q2区/病毒学二区）
7. Zhijiang Miao1, Zhenrong Xie1, Li Ren, Qiuwei Pan*. Hepatitis D: advances and challenges,Chinese Medical Journal, 2022 Apr 5;135(7):767-773. (Invited Review). (IF=6.2; JCR Q3/医学三区)
8. Zhijiang Miao, Yunlong Li, Peifa Yu, Bingting Yu, Maikel P. Peppelenbosch and Qiuwei Pan*, The dynamics of hepatitis delta virus prevalence and its potential association with hepatitis B virus vaccination,Clinics and Research in Hepatology and Gastroenterology, 2021 May;45(3):101677.（IF=3.2; JCR Q3区/胃肠肝病学四区）
9. Zhijiang Miao1, Li Gao1, Yindi Song, Ming Yang, Mi Zhang, Jincheng Lou, Yue Zhao, Xicheng Wang, Yue Feng*, Xingqi Dong* and Xueshan Xia*. Prevalence and clinical impact of human pegivirus-1 infection in HIV-1-infected individuals in Yunnan, China.Viruses, 2017 Feb 15;9(2):28.（IF=3.8; JCR Q2区/微病毒学三区）
10. Zhijiang Miao1, Zhenrong Xie1, Jing Miao, Jieyu Ran, Yue Feng* and Xueshan Xia*, Regulated Entry of Hepatitis C Virus into Hepatocytes. Viruses, 2017 May 9;9(5):100.（IF=3. 8; JCR Q2区/微病毒学三区）
11. Peifa Yu,Zhijiang Miao, Yang Li, Maikel P. Peppelenbosch, Qiuwei Pan*. cGAS-STING Effectively Restricts Murine Norovirus Infection But Antagonizes the Antiviral Action of N-terminus of RIG-I in Mouse Macrophages.Gut Microbes, 2021 Jan-Dec;13(1):1959839. (IF=9.4; JCR Q1区/医学一区Top)
12. Yunlong Li,Zhijiang Miao, Pengfei Li, Ruyi Zhang , Denis E Kainov , Zhongren Ma , Robert A de Man, Maikel P Peppelenbosch and Qiuwei Pan*, Ivermectin effectively inhibits hepatitis E virus replication, requiring the host nuclear transport protein importin α1.Archives of Virology, 2021.（IF=2.6; JCR Q3区/病毒学四区）
13. Ling Wang, Jiaye Liu,Zhijiang Miao, Qiuwei Pan* and Wanlu Cao*. Lipid droplets and their interactions with other organelles in liver diseases.The International Journal of Biochemistry & Cell Biology，2021.（IF=5.1; JCR Q2区/细胞生物学三区）
14. Peifa Yu, Yang Li, Yunlong Li,Zhijiang Miao, Maikel P. Peppelenbosch and Qiuwei Pan*. Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.Journal of Biological Chemistry, 2020.（IF=5.2; JCR Q2区/生物学二区Top）
15. Peifa Yu, Yang Li, Yunlong Li,Zhijiang Miao, Yining Wang, Maikel P. Peppelenbosch and Qiuwei Pan*. Murine norovirus replicase augments RIG-I-like receptors-mediated antiviral interferon response.Antiviral Research, 2020.（IF=6.0; JCR Q1/2区/病毒学药学二区）
16. Xumin Ou, Buyun Ma, Ruyi Zhang,Zhijiang Miao, Anchun Cheng, Maikel P. Peppelenbosch and Qiuwei Pan*. A simplified qPCR method revealing tRNAome remodeling upon infection by genotype 3 hepatitis E virus.FEBS letters, 2020.（IF=4.1; JCR Q3区/病毒学四区）
17. Yindi Song1, Yue Feng1,Zhijiang Miao, Binghui Wang, Ming Yang, A-Mei Zhang, Li Liu and Xueshan Xia*. Near-Full- Length Genome Sequences of a Novel Hiv-1 Circulating Recombinant Form, Crf01_Ae/B'/C（Crf78_Cpx）, in Yunnan, China.AIDS research and human retroviruses, 2016.（IF=2.2; JCR Q4区/病毒学四区）
18. Yanping Li1, Jing Miao1,Zhijiang Miao, Yindi Song, Min Wen, Ya Zhang, Shimin Guo, Yuan Zhao, Yue Feng* and Xueshan Xia*. Identification of a Novel HIV Type 1 Circulating Recombinant Form（CRF86_BC）Among Heterosexuals in Yunnan, China.AIDS research and human retroviruses, 2016.（IF=2.2; JCR Q4区/病毒学四区）
19. Li Ren, Binghui Wang,Zhijiang Miao, Pan Liu, Shiyi Zhou, Yun Feng, Shuting Yang, Xueshan Xia* and Kunhua Wang*, A correlation analysis of HHV infection and its predictive factors in an HIV-seropositive population in Yunnan, China,Journal of Medical virology, 2019.（IF=2.3; JCR Q4区/病毒学四区）
7、获得奖励
1. 2022.11“农行杯”第八届云南省互联网+大学生创新创业大赛金奖指导教师。
