王海燕
学历：博士
专家类别（职称）：助理研究员
邮箱：wanghaiyan@kmmu.edu.cn
通讯地址：云南省昆明市呈贡区雨花街道春融西路1168号
邮编：650500
简历
教育经历
（1）2019-09至2023-06，中南大学，病理学与病理生理学，博士
（2）2016-09至2019-06，中南大学，药理学，硕士
（3）2012-09至2016-06，南昌大学，制药工程，学士
工作经历
2023-09-至今，澳洲5·（中国）集团有限公司,，生物医学工程研究院，助理研究员
研究方向
G蛋白偶联受体与消化道肿瘤的分子机制与靶向药物研究
研究成果（论文、专利、专著等）
[1] Wang H, Cheng Y, Mao C, et al. Emerging mechanisms and targeted therapy of ferroptosis in cancer. Mol Ther. 2021 Jul 7;29(7):2185-2208.
[2]Wang HY#, Yu P#, Chen XS, et al. Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction. Acta Pharmacol Sin. 2022 Jun;43(6):1594-1604.
[3] Yu P#,Wang HY#, Tian M, et al. Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro. Acta Pharmacol Sin. 2019 Sep;40(9):1237-1244.
[4] Chen L, Cai QD, Yang R,Wang HY, Huli Ling, et al. GINS4 suppresses ferroptosis by antagonizing p53 acetylation with Snail. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15): e2219585120.
[5] Yan BK, Guo JX, Wang ZL, Jieling N,Haiyan W, et al. The ubiquitin-specific protease 5 mediated deubiquitination of LSH links metabolic regulation of ferroptosis to hepatocellular carcinoma progression. MedComm (2020). 2023 Jul 22;4(4):e337.
[6] Yao L, Guo JX, Chen JL, Sun JY, Wang HY, Peng X, et al. GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer. Signal Transduct Target Ther (IF= 38.104). 2023 Feb 1;8(1):48.
